CompletedNot Applicable

High Molecular Weight Hyaluronic Acid, α-lipoic Acid, Magnesium, Vitamin B6 and Vitamin D, in the Prevention of Spontaneous Abortion

Italy100 participantsStarted 2022-09-01

Plain-language summary

The study aims to verify if the association of high molecular weight hyaluronic acid, α-lipoic acid (ALA), magnesium, vitamin B6 and vitamin D, reduces the risk of miscarriage in patients at risk.

Who can participate

Age range18 Years – 45 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * two or more previous spontaneous first trimester abortions without apparent risk factors (idiopathic polyabortion) * Endocrinopathies * Autoimmune diseases * Thrombophililic or coagulation diseases Exclusion Criteria: * Multiple pregnancies * Presence of genetic abnormalities of one or both partners leading to increased risk of fetal aneuploidies * Presence of Mullerian abnormalities in the uterus * Symptoms present at recruitment such as pelvic pain or metrorrhagia

What they're measuring

Incidence of metrorrhagia and/or pelvic pain in the first trimester of gestation.

Timeframe: 3 months

Trial details

NCT IDNCT05449171

SponsorLo.Li.Pharma s.r.l

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2023-09-01

View on ClinicalTrials.gov More Abortion, Spontaneous trials