The aim of this initial investigational study is to compare the effect of desloratadine on the inflammatory responses to heat stress in firefighters exercising in their personal protective equipment.
Age range
19 Years – 50 Years
Sex
MALE
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Change in serum cortisol
Timeframe: Before, immediately following, and 2-hours following exertional heat strain
Change in serum interleukin-6 and ELISA
Timeframe: Before, immediately following, and 2-hours following exertional heat strain
Change in serum c-reactive protein
Timeframe: Before, immediately following, and 24, 48, and 72-hours following exertional heat strain
Change in serum tumor necrosis factor alpha
Timeframe: Before, immediately following, and 2-hours following exertional heat strain