Factors in Learning And Plasticity: Healthy Vision (NCT05439759) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Factors in Learning And Plasticity: Healthy Vision
United States120 participantsStarted 2022-10-24
Plain-language summary
A greater understanding of plasticity after central vision loss can inform new therapies for treating low vision and has the potential to benefit millions of individuals suffering from low vision. The treatment of low vision is particularly relevant to the mission of the National Eye Institute (NEI) to support research on visual disorders, mechanisms of visual function, and preservation of sight. The comparison of different training and outcome factors is in line with the National Institute of Mental Health (NIMH) Research Domain Criteria (RDOC) framework and studies in an aging population are consistent with the mission of the National Institute on Aging (NIA).
Who can participate
Age range
18 Years – 30 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Aged 18-30
* Corrected vision (20/40 or better)
* No reported incidence of retinal pathology.
Exclusion Criteria:
* Pacemaker or any ferromagnetic metal implanted in their body
* Metal of any type implanted in their head (limited dental work is acceptable)
* Claustrophobia
* Needing non-standard glasses (other than the simple MR-compatible glasses that can be supplied) for best-corrected distance vision
* Being hearing-impaired
* Weight over 300 pounds
* Maximum body girth over 60 inches
* Previous serious head injury
* Presence of hallucinations or delusions
* Excessive old, or colorful tattoos, especially near the head
* Pregnancy
* Braces/permanent retainer
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change from Baseline Radial Bias from the Crowding Task after completion of Training at approximately 7 weeks
Timeframe: Baseline and Within 3 weeks of training completion, training is complete 7 weeks from baseline on average
2
Change from Baseline Saccadic Precision after Completion of Training at approximately 7 weeks
Timeframe: Baseline and Within 3 weeks of training completion, training is complete 7 weeks from baseline on average
3
Change from Baseline Fixation Stability after Completion of Training at approximately 7 weeks
Timeframe: Baseline and Within 3 weeks of training completion, training is complete 7 weeks from baseline on average