CompletedNot Applicable

A Prospective Study to Evaluate the Correlation Between Oculometric Measurements and Clinical Endpoints in PD Patients

Israel465 participantsStarted 2022-08-20

Plain-language summary

This is a prospective study in a cohort of about 500 patients with Idiopathic Parkinson's disease, examined routinely in the neurological outpatient clinic. This study aims to evaluate the correlation between oculometric measures and clinical endpoints. Subjects will be evaluated following a physician examination.The evaluations will include MDS-UPDRS examination, as well as an oculometric evaluation for eye movements. In addition, 500 healthy subjects will be evaluated.

Who can participate

Age range18 Years – 85 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

PD patients: Inclusion Criteria: * Men and women with idiopathic PD (Hoehn \& Yahr scale 1-5) * Age between 18 and 85 years old * Normal or corrected vision * Ability to follow instructions * Willing and able to sign an informed consent form Exclusion Criteria: * Inability to sit for 20 minutes on a chair in a calm manner * Personal or 1st degree relative history of epilepsy * Additional neurological diseases * Drug or alcohol abuse Healthy subjects: Inclusion Criteria: * Age between 18 and 85 years old * Normal or corrected vision * Ability to follow instructions * Willing and able to sign an informed consent form Exclusion Criteria * Inability to sit for 20 minutes on a chair in a calm manner * Personal or 1st degree relative history of epilepsy * Neurological diseases * Drug or alcohol abuse

What they're measuring

Correlation between MDS-UPDRS score and its parts with NeuraLight oculometric measurements

Timeframe: 12 months

Feasibility of using NeuraLight system to capture oculometric measures in a cohort of PD patients and healthy subjects

Timeframe: 12 months

Comparison of NeuraLight extracted oculometric measures with a validated eye-tracking system

Timeframe: 12 months

Trial details

NCT IDNCT05437003

SponsorNeuraLight

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2024-02-15

View on ClinicalTrials.gov More Idiopathic Parkinson Disease trials

Plain-language summary

Who can participate

Age range18 Years – 85 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Correlation between MDS-UPDRS score and its parts with NeuraLight oculometric measurements

Timeframe: 12 months

Feasibility of using NeuraLight system to capture oculometric measures in a cohort of PD patients and healthy subjects

Timeframe: 12 months

Comparison of NeuraLight extracted oculometric measures with a validated eye-tracking system

Timeframe: 12 months