The Effect of Interscalene Block on Intracranial Pressure

Inclusion Criteria: * Patients who had elective humeral fracture and open rotator-cuff surgery, * Patients aged 18-85 years, * Patients have ASA I-II anesthesia risk according to the American Society of Anesthesiologists (ASA) risk classification, * Patients that gave consent for participation in the study will be included. Exclusion Criteria: * Patients who do not give consent to the study, * Patients with infection and open wounds in the area of skin puncture and eyelids, * Patients have any history of intracranial pathology, * Patients have nerve blockade contraindications such as coagulation disorder and antithrombotic-anticoagulant use, * Patients have a history of allergy to one of the study drugs, * Patients have a body mass index over 35 kg/m2, * Patients with contralateral pneumothorax, * Patients with severe respiratory distress, * Patients with uncontrolled hypertension, * Patients with acute or chronic eye disease, * Patients with previous eye surgery, * Patients using a beta-blocker known to increase intraocular pressure, * Patients using calcium channel blockers, statins and nitrates, * Patients in need of intraoperative sedation, * Patients who develope any complications (hoarseness, horner's syndrome, respiratory distress, local anesthetic toxicity) due to ISBP block will be excluded from the study.