The Effects of Nicardipine and Esmolol Applied for Controlled Hypotension

Inclusion Criteria: * Between 18-60 years of age, * ASA I-II, * undergoing elective rhinoplasty surgery, * it was decided to apply controlled hypotension, * BMI (body mass index) between 18-25 kg/m2, * informed about the subject and * patients with written consent Exclusion Criteria: * ASA III-IV patients, * hypertension disease, * using anticoagulant medication, * pregnancy, * kidney failure, * bleeding diathesis, * active infection, * allergy to drugs to be used, * BMI≥30, * refusing to participate in the study, * hypothermic, * patients taking antibiotics, anticonvulsants, antiarrhythmics, cholinesterase inhibitors