CompletedNot Applicable

Exploring the Cortical Hemodynamic Variability of Four Weeks iTBS on a Healthy Participant: a Case Study

Hong Kong1 participantsStarted 2022-08-15

Plain-language summary

This study will investigate the effect of caffeine and time of day on brain excitability using excitatory brain stimulation. The investigators will recruit a healthy participant and conduct a concurrent iTBS/fNIRS protocol for 20 consecutive sessions over four weeks with or without caffeine consumption before the stimulation. Moreover, the experiment will be conducted at different times of the day (morning or afternoon)

Who can participate

Age range18 Years – 35 Years

SexALL

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Inclusion Criteria: * Right-handed Exclusion Criteria: * history of epilepsy, seizures, or convulsions * current or past diagnosis of neurological disorders, such as head injuries, strokes, encephalitis, epilepsy, Parkinson's, or Alzheimer's * current or past diagnosis of psychiatric disorders, such as depression, anxiety, schizophrenia, or autism * with metal implants, such as a cochlear implant, neurostimulator, or cardiac pacemaker

What they're measuring

Oxygenated hemoglobin (HbO) change compared to baseline

Timeframe: During and post TBS-fNIRS measurement, up to 1 month

Trial details

NCT IDNCT05427565

SponsorThe Hong Kong Polytechnic University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-09-09

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