Laparoscopic Transversus Abdominis Plane Block (LTAP) for Appendicectomy Versus Standard Port Sit… (NCT05427266) | Clinical Trial Compass
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Laparoscopic Transversus Abdominis Plane Block (LTAP) for Appendicectomy Versus Standard Port Site Treatment
172 participantsStarted 2022-07
Plain-language summary
This study aims to compare Laparoscopic assisted LTAP (Transversus Abdominis Plane) to standard port-site infiltration in terms of post-operative visual analogue scores (VAS) for pain at 3, 6, 12 and 24 hours following laparoscopic appendicectomy Tap Block is a standard conventional analgesia protocol for laparoscopic appendicitis used in Beaumont Hospital, and other hospitals throughout Ireland.
The medicinal product for both groups is the same - Bupivacaine. The mode of administration is what this study is reviewing: Control group (Standard port site infiltration) and Study Group - Laparoscopic Transversus Abdominis Plane Block
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Provide signed and dated informed consent form
* Willing to comply with all study procedures and be available for follow up telephone follow up
* Male or female, aged over 18
* Diagnosed either clinically or radiologically (CT/US/MRI) with appendicitis
* Uncomplicated or complicated appendicitis
* Undergoing laparoscopic appendicitis surgery only
* Must be fluent in English in order to complete telephone follow up questionnaire
* Fulfillment of each criteria must be clearly evidenced (in lab reports or correspondence) and/or documented in the medical records.
Exclusion Criteria:
* Male or female under the age or 18
* Laparoscopic converted to open appendicectomy (during surgical procedure)
* Open appendicectomy (planned)
* Pregnancy.
* Females must not be breastfeeding
* Known allergic reactions to components of the study product(s) )
* Not fluent in English - which would prevent participants to complete follow up telephone questionnaire
* Malignant appendicitis
* Spinal Anaesthesia, Epidural analgesia catheter or injections, Post-operative requirements for patient controlled analgesia (PCA)
* Right hemicolectomy or any concomitant or simultaneous intervention
* Allergy or hypersensitivity to any of the components of Bupivacaine
* Presence of any other illness or condition that renders the patient unsuitable for trial participation in the opinion of the investigator
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Assessing pain post laparoscopic appendicectomy using Visual analogue score (VAS score)
Timeframe: Assessing change in pain score post extubation at 3 hours, 6 hours, 12 hours and 24 hours.