Role of Peanuts in Healthy Weight Gain in Athletic Individuals (NCT05426109) | Clinical Trial Compass
CompletedNot Applicable
Role of Peanuts in Healthy Weight Gain in Athletic Individuals
United States33 participantsStarted 2021-11-22
Plain-language summary
Many athletes and military personnel desire weight gain primarily as lean mass to improve performance and effectiveness in military/sport endeavors. While much is known about the energy restriction required to reduce body weight, very little is understood about energy and macronutrients needed to promote healthy gains in body weight and lean mass. Typically, athletes are encouraged to increase calorie intake by \~500 kcal/day with an emphasis on adequate protein and carbohydrate, and judicious inclusion of healthy fat-containing calorically-dense foods, including peanuts and peanut butter. This study proposes to evaluate the effect of a 10-week diet and exercise regimen designed to promote healthy weight gain. This will include increasing energy intake by 500 additional kcal/day (above weight maintenance diet) through daily provision of either peanut-based whole foods/snacks (peanut group) or a similar, high-carbohydrate, peanut-free snack (control group) along with a supervised strength training regimen. Results will serve as an important first step in helping understand the gaps in knowledge related to healthy weight gain, designing better weight gain meal plans, not only in athletes and military personnel, but also in clinical populations where promotion of weight gain is advocated.
Who can participate
Age range
18 Years – 40 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Interested in gaining 5 pounds of body weight to enhance effectiveness in sport, fitness, or military training/competition.
* Willing to eat 500 kcal/d and weight train 3x/wk for 10 weeks
* Have weight trained in the past 12 months
* Not taking medications or dietary supplements that influence study results
* Non-smoker
* Without any major medical problems (including high blood pressure or coronary heart disease)
Exclusion Criteria:
* Nut, peanut, tree nut or legume allergy
* No weight training experience
* Orthopedic limitations that affect ability to weight train
* Currently taking dietary supplements or prescribed pharmacological agents that may affect lean tissue accretion
* Current or past anabolic steroid use
* Have a history of or current signs of disordered eating
* Pregnant
* Abnormal levels of thyroid stimulating hormone or hemoglobin, serum lipids (e.g., fasting triglycerides \>150 mg/dL and/or total cholesterol \>200 mg/dL)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Total Body Mass (Weight)
Timeframe: 1-min laboratory measurement assessed at the baseline, 3-wk, 7-wk, and 11-week test sessions.
2
Change in Lean Body Mass
Timeframe: 10-min laboratory measurement assessed at the baseline, 3-wk, 7-wk and 11-week test sessions.
Trial details
NCT IDNCT05426109
SponsorVirginia Polytechnic Institute and State University