CompletedNot Applicable

Effects of Collagen Peptide Supplementation on Muscle and Tendon Damage and Function

Belgium22 participantsStarted 2021-04-12

Plain-language summary

The aim of the study is to investigate the acute and short-term effects of collagen peptides (Collagen Peptan) on muscle and connective tissue during an eccentric overload training period. Currently, all studies investigating the effects of post-exercise collagen supplementation did this in the absence of whey proteins, which are part of the standard recommendations for post-exercise recovery. The investigators will therefore investigate whether the combined intake of whey proteins and collagen peptides ensures a better recovery of exercise performance and whether it can prevent or reduce symptoms of muscle and tendon overload during a three-week eccentric overload training period (n = 22).

Who can participate

Age range

18 Years – 30 Years

Sex

MALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Sports participation, including general fitness training, between 2 and 5 hours max per week * Body mass index between 18.5 and 25 Exclusion Criteria: * Any kind of injury/pathology that is a contra-indication to perform high-intensity exercise - Intake of any medication or nutritional supplement that could impact muscle protein synthesis and/or exercise performance during the period of the study * Intake of any whey protein, casein of branched-chain amino acid (BCAA) supplements from 1 month prior to the start of the study * Blood donation within 3 months prior to the start of the study * Smoking * Current participation in another research trial * Any other argument to believe that the subject is unlikely to successfully complete the full study

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in countermovement jump performance

Timeframe: Pretest - 48 hours after the first training session (day 3 of training intervention) - Posttest (day 22 of training intervention)

Change in maximal isometric knee-extension force of the right leg

Timeframe: Pretest - 48 hours after the first training session (day 3 of training intervention) - Posttest (day 22 of training intervention)

Change in anteroposterior thickness of the right patellar tendon

Timeframe: Pretest - 48 hours after the first training session (day 3 of training intervention) - Posttest (day 22 of training intervention)

Change in neovascularization of the right patellar tendon

Timeframe: Pretest - 48 hours after the first training session (day 3 of training intervention) - Posttest (day 22 of training intervention)

Trial details

NCT IDNCT05425407

SponsorKU Leuven

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-05-30

View on ClinicalTrials.gov More Exercise trials

Plain-language summary

Who can participate

Age range

18 Years – 30 Years

Sex

MALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change in countermovement jump performance

Timeframe: Pretest - 48 hours after the first training session (day 3 of training intervention) - Posttest (day 22 of training intervention)

Change in maximal isometric knee-extension force of the right leg

Timeframe: Pretest - 48 hours after the first training session (day 3 of training intervention) - Posttest (day 22 of training intervention)

Change in anteroposterior thickness of the right patellar tendon

Timeframe: Pretest - 48 hours after the first training session (day 3 of training intervention) - Posttest (day 22 of training intervention)

Change in neovascularization of the right patellar tendon

Timeframe: Pretest - 48 hours after the first training session (day 3 of training intervention) - Posttest (day 22 of training intervention)