CompletedNot Applicable

Treatment of Non-Anemic Iron Deficiency in Pregnancy

United States150 participantsStarted 2022-08-12

Plain-language summary

The objective is to investigate the treatment of non-anemic iron deficiency (NAID) and the impact on development of anemia later in pregnancy. Anemia in the third trimester has been identified as a risk factor for maternal and fetal morbidity that might lead to mortality. Due to the high incidence of NAID in pregnancy, there is an opportunity for early screening and treatment to decrease progression to anemia. The primary aim of this study is to establish if treatment of NAID will result in higher third trimester hemoglobin values and decrease incidence of anemia at term.

Who can participate

Age range18 Years – 55 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * English speaking * age 18-55 * less than 20 weeks gestational age * low ferritin level (\<30mcg/L) in the first trimester * normal hemoglobin level (\>11g/dL) in the first trimester Exclusion Criteria: * Women with anemia diagnosed in the first trimester (HgB ≤11 g/dL) * Women with antepartum iron supplementation, except prenatal vitamin, within 3 months * Women with iron overload or hypersensitivity * Women with significant vaginal bleeding prior to enrollment * Women with chronic illness: SLE, hemoglobinopathies, HIV, inflammatory bowel disease, active cancer, prior bariatric surgery

What they're measuring

Delivery admission hemoglobin

Timeframe: From date of randomization until to 42 weeks

Third trimester hemoglobin

Timeframe: 28 weeks to 36 weeks

Trial details

NCT IDNCT05423249

SponsorStony Brook University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-11-01

View on ClinicalTrials.gov More Non-anemic Iron Deficiency trials