CompletedNot Applicable

Rebreathing-induced Hypoxia and Glucose Levels

United States20 participantsStarted 2021-10-21

Plain-language summary

The aim of this research project is to determine the effect of repeated maximal voluntary apneas on glucose uptake during an oral glucose tolerance test in healthy individuals, individuals with prediabetes and patients with type 2 diabetes.

Who can participate

Age range18 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Men and women aged 18 to 80 years old Exclusion Criteria: * Have uncontrolled stage 2 hypertension (˃140/90 mmHg) * Are smokers * Are pregnant * Have a history of cardiovascular disease or indication of cardiovascular disease such as myocardial infarction, left ventricular hypertrophy, ischemic heart disease (or prior ischemia), stroke, and/or other vascular disease * Have a history of lung disease * Are taking insulin or more than one antihypertensive medication * Have poorly controlled diabetes: HbA1c levels ˃ 9% * Have been previously diagnosed with diabetic complications (nephropathy, neuropathy, retinopathy) by their family doctor

What they're measuring

Change in plasma glucose levels

Timeframe: Collected at min 0, 30, 60, 90 and 120 minutes of the oral glucose tolerance test

Trial details

NCT IDNCT05422430

SponsorUniversity of Texas at Austin

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-09-04

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