The Purpose of This Study is to Determine the Frequency of Colorectal Cancer in Male and Female Endurance Athletes Between the Ages of 35 and 50

Inclusion Criteria: * Adult males and females 35-50 years of age * Male and female self-reported endurance athletes, defined by at least one of the following: * Run at least two races of 50 miles or more * Run 5 races of 26.2 miles or more * Ability to complete testing in the protocol and make study visits * Able and willing to consent to protocol Exclusion Criteria: * Known or suspected history of inflammatory bowel disease, familial adenomatous polyposis (FAP), or Lynch Syndrome * Concomitant illness that would prevent adequate patient assessment or in the investigators' opinion pose an added risk for study participants. * Anticipated poor compliance * Prisoners or subjects who are involuntarily incarcerated * Persons with decisional incapacity/cognitive impairment * Any history or evidence of severe illness or any other condition that would make the patient, in the opinion of the investigator unsuitable for the study * Subject is involved with a worker's compensation, personal injury, or other legal matters related to their health * Subject is enrolled in a separate interventional clinical trial