Active — Not RecruitingNot Applicable

Evaluation of Lifestyle Modification on Cardiovascular Risk

United Kingdom60 participantsStarted 2022-08-15

Plain-language summary

This study proposes to examine the independent and combined effects of an 8-week home-based, equipment-free HIIT exercise intervention with/without Mediterranean diet through ghrelin-mediated alteration in overweight and obese metabolic women to improve cardiovascular-risk related markers and metabolic risk factors.

Who can participate

Age range45 Years – 65 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Female * Participants \>45-65 years of age * Body mass index (BMI) \>25.0 - 35.0 * Postmenopausal (with spontaneous amenorrhea for the last 12 months) * Healthy (no known diseases) * Physically inactive (IPAQ score - category I and not engaged in at least 60 min/week of structured exercise during the previous 6 months) * Generally well enough to exercise. Exclusion Criteria: * Any inclusion criteria not met * Abnormal ECG * Current smokers * Current or history of substance abuse and/or excess alcohol intake * Cardiovascular disease * Cancer * Gastrointestinal disease e.g. inflammatory bowel disease or irritable bowel syndrome * Kidney disease * Liver disease * Pancreatitis * On hormone therapy for \<6 months * Prescribed anti-hypertensive or beta-blocker medication