CompletedNot Applicable

Autonomic Neuromodulation by Transcutaneous Nerve Stimulation in Acute Ischaemic Stroke.

United Kingdom36 participantsStarted 2023-04-26

Plain-language summary

Autonomic modulation by transcutaneous vagal nerve stimulation in acute ischaemic stroke requiring mechanical thrombectomy: a phase IIa, sham controlled randomised trial.

Who can participate

Age range18 Years – 95 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Undergoing mechanical thrombectomy for acute ischaemic stroke requiring general or sedation. * Established hypertensive and/or hypertensive on admission for mechanical thrombectomy \[systolic BP \>140mmHg; diastolic BP \>80mmHg\] Exclusion Criteria: * Current participation in a clinical trial of a treatment with a similar biological mechanism. * Previous enrolment into VANS trial. * Anatomical or other contraindication to trans-cutaneous auricular sensory stimulation * Pregnancy.

What they're measuring

Blood Pressure Variability

Timeframe: 0-24h after mechanical thrombectomy

Trial details

NCT IDNCT05417009

SponsorQueen Mary University of London

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-07-21

Results submitted2024-10-03

View on ClinicalTrials.gov More Ischemic Stroke trials