CompletedNot Applicable

BEAST: A Pilot Trial

United States15 participantsStarted 2022-09-01

Plain-language summary

This pilot study trial will test the acceptability, feasibility, and usability of a brief enhanced anxiety sensitivity treatment to reduce anxiety sensitivity and functional impairment in Veterans.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Are English-speaking * Score equal to or greater than 9 on the SSASI indicating elevated anxiety sensitivity * Score equal to or greater than 5 on the WHODAS 2.0 Exclusion Criteria: * Veterans with cognitive impairment as measured scoring equal to or greater than 11 on the Blessed * Orientation-Memory-Concentration Test * Veterans without access to a smartphone * Veterans with significant medical or psychiatric conditions that may limit participation, including: * severe documented schizophrenia * an ongoing active psychotic or manic state * an imminent suicide crisis will be excluded from our study and provided the appropriate referral

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Mean Change in Anxiety Sensitivity

Timeframe: From baseline to post-intervention (two-weeks after virtual treatment session)

Program Satisfaction

Timeframe: Post-intervention (two weeks after virtual treatment session)

Mean Change in Functional Impairment

Timeframe: From baseline to post-intervention (two-weeks after virtual treatment session)

Trial details

NCT IDNCT05416203

SponsorVA Office of Research and Development

Sponsor typeFED

Study typeINTERVENTIONAL

Primary completion2024-05-31

Results submitted2025-05-22

View on ClinicalTrials.gov More Anxiety Sensitivity trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Mean Change in Anxiety Sensitivity

Timeframe: From baseline to post-intervention (two-weeks after virtual treatment session)

Program Satisfaction

Timeframe: Post-intervention (two weeks after virtual treatment session)

Mean Change in Functional Impairment

Timeframe: From baseline to post-intervention (two-weeks after virtual treatment session)