Degenerative lumbar spinal diseases have become a common health problem and the most frequent indication for spinal surgery in elderly individuals. It mainly contain lumbar spinal stenosis and spondylolisthesis, occurs in most people over 60 years of age, and patients primarily diagnosed with lumbar degenerative disease are more likely to have osteoporosis. Our study was to explore denosumab effect on bone quality and functional status in osteopenia patients with lumbar degenerative diseases after lumbar fusion surgery.
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Lumbar bone mineral density (BMD)
Timeframe: up to 12 months
Total hip BMD
Timeframe: up to 12 months
Femoral neck BMD
Timeframe: up to 12 months
Type 1 n-terminal propeptide P1NP
Timeframe: up to 12 months
C-terminal crosslinking type 1 collagen terminal peptide CTX
Timeframe: up to 12 months
Visual analog scale (VAS) back
Timeframe: up to 12 months
VAS leg
Timeframe: up to 12 months