The purpose of our study is to examine the effect of platelet-rich-plasma (PRP) injection on the short-term resolution of post-injury inflammation (biomarkers) and improvement in joint function in patients with acute ACL injury. This RCT has been powered based on the questionnaire KOOS Jr. but it is considered a 'pilot study' in terms of the lab analysis proposed.
Age range
14 Years – 50 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Platelet count (Thousand/uL)
Timeframe: Baseline
Platelet count (Thousand/uL)
Timeframe: during the procedure
Knee Injury and Osteoarthritis Outcome (KOOS-JR)
Timeframe: Baseline
Knee Injury and Osteoarthritis Outcome (KOOS-JR)
Timeframe: during the procedure
Knee Injury and Osteoarthritis Outcome (KOOS-JR)
Timeframe: 2 weeks post-op
Knee Injury and Osteoarthritis Outcome (KOOS-JR)
Timeframe: 6 weeks post-op
Knee Injury and Osteoarthritis Outcome (KOOS-JR)
Timeframe: 6 months post-op
Knee Injury and Osteoarthritis Outcome (KOOS-JR)
Timeframe: 12 months post-op
Knee Injury and Osteoarthritis Outcome (KOOS-JR)
Timeframe: 24 months post-op
Numeric Pain Rating Scale (NPRS)
Timeframe: Baseline
Numeric Pain Rating Scale (NPRS)
Timeframe: during the procedure
Numeric Pain Rating Scale (NPRS)
Timeframe: 6 weeks post-op
Numeric Pain Rating Scale (NPRS)
Timeframe: 6 months post-op
Numeric Pain Rating Scale (NPRS)
Timeframe: 12 months post-op
Numeric Pain Rating Scale (NPRS)
Timeframe: 24 months post-op
Patient-Reported Outcomes Measurement Information System 10 (PROMIS-10)
Timeframe: Baseline
Patient-Reported Outcomes Measurement Information System 10 (PROMIS-10)
Timeframe: during the procedure
Patient-Reported Outcomes Measurement Information System 10 (PROMIS-10)
Timeframe: 2 weeks post-op
Patient-Reported Outcomes Measurement Information System 10 (PROMIS-10)
Timeframe: 6 weeks post-op
Patient-Reported Outcomes Measurement Information System 10 (PROMIS-10)
Timeframe: 6 months post-op
Patient-Reported Outcomes Measurement Information System 10 (PROMIS-10)
Timeframe: 12 months post-op
Patient-Reported Outcomes Measurement Information System 10 (PROMIS-10)
Timeframe: 24 months post-op
Single Assessment Numeric Evaluation (SANE)
Timeframe: Baseline
Single Assessment Numeric Evaluation (SANE)
Timeframe: during the procedure
Single Assessment Numeric Evaluation (SANE)
Timeframe: 2 weeks post-op
Single Assessment Numeric Evaluation (SANE)
Timeframe: 6 weeks post-op
Single Assessment Numeric Evaluation (SANE)
Timeframe: 6 months post-op
Single Assessment Numeric Evaluation (SANE)
Timeframe: 12 months post-op
Single Assessment Numeric Evaluation (SANE)
Timeframe: 24 months post-op