The purpose of our study is to examine the effect of platelet-rich-plasma (PRP) injection on the short-term resolution of post-injury inflammation (biomarkers) and improvement in joint function in patients with acute ACL injury. This RCT has been powered based on the questionnaire KOOS Jr. but it is considered a 'pilot study' in terms of the lab analysis proposed.
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Platelet count (Thousand/uL)
Timeframe: Baseline
Platelet count (Thousand/uL)
Timeframe: during the procedure
Knee Injury and Osteoarthritis Outcome (KOOS-JR)
Timeframe: Baseline
Knee Injury and Osteoarthritis Outcome (KOOS-JR)
Timeframe: during the procedure
Knee Injury and Osteoarthritis Outcome (KOOS-JR)
Timeframe: 2 weeks post-op
Knee Injury and Osteoarthritis Outcome (KOOS-JR)
Timeframe: 6 weeks post-op
Knee Injury and Osteoarthritis Outcome (KOOS-JR)
Timeframe: 6 months post-op
Knee Injury and Osteoarthritis Outcome (KOOS-JR)
Timeframe: 12 months post-op
Knee Injury and Osteoarthritis Outcome (KOOS-JR)
Timeframe: 24 months post-op
Numeric Pain Rating Scale (NPRS)
Timeframe: Baseline
Numeric Pain Rating Scale (NPRS)
Timeframe: during the procedure
Numeric Pain Rating Scale (NPRS)
Timeframe: 6 weeks post-op
Numeric Pain Rating Scale (NPRS)
Timeframe: 6 months post-op
Numeric Pain Rating Scale (NPRS)
Timeframe: 12 months post-op
Numeric Pain Rating Scale (NPRS)
Timeframe: 24 months post-op
Patient-Reported Outcomes Measurement Information System 10 (PROMIS-10)
Timeframe: Baseline
Patient-Reported Outcomes Measurement Information System 10 (PROMIS-10)
Timeframe: during the procedure
Patient-Reported Outcomes Measurement Information System 10 (PROMIS-10)
Timeframe: 2 weeks post-op
Patient-Reported Outcomes Measurement Information System 10 (PROMIS-10)
Timeframe: 6 weeks post-op
Patient-Reported Outcomes Measurement Information System 10 (PROMIS-10)
Timeframe: 6 months post-op
Patient-Reported Outcomes Measurement Information System 10 (PROMIS-10)
Timeframe: 12 months post-op
Patient-Reported Outcomes Measurement Information System 10 (PROMIS-10)
Timeframe: 24 months post-op
Single Assessment Numeric Evaluation (SANE)
Timeframe: Baseline
Single Assessment Numeric Evaluation (SANE)
Timeframe: during the procedure
Single Assessment Numeric Evaluation (SANE)
Timeframe: 2 weeks post-op
Single Assessment Numeric Evaluation (SANE)
Timeframe: 6 weeks post-op
Single Assessment Numeric Evaluation (SANE)
Timeframe: 6 months post-op
Single Assessment Numeric Evaluation (SANE)
Timeframe: 12 months post-op
Single Assessment Numeric Evaluation (SANE)
Timeframe: 24 months post-op