Efficacy and Safety of Etomidate Sedation in Gastric Endoscopic Submucosal Dissection (NCT05407870) | Clinical Trial Compass
CompletedNot Applicable
Efficacy and Safety of Etomidate Sedation in Gastric Endoscopic Submucosal Dissection
South Korea138 participantsStarted 2022-06-09
Plain-language summary
During endoscopy, the patient is sedated to relieve pain and improve the ease of the procedure. Sedation endoscopy using propofol is effective, but has the disadvantage that cardiopulmonary side effects are frequently observed. However, etomidate is known to have hemodynamic and respiratory stability.The purpose of this study was to compare the efficacy and safety of etomidate and propofol in sedated gastric endoscopic submucosal dissection.
Who can participate
Age range
19 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 19-80
* American Society of Anesthesiologists Physical Status Classification System (ASA) score of I, II, III
* Scheduled endoscopy
Exclusion Criteria:
* Pregnancy
* Previous study History of hypersensitivity to drugs or substances containing soy or egg ingredients
* Those who think that tracheal intubation will be difficult
* Obstructive sleep apnea
* History of side effects from previous sedatives
* People with severe liver disease, kidney disease, or heart disease
* Those who want a non-sleeping endoscope
* A person who refuses to provide consent
* SBP \< 80mmHg or SpO2 \< 90%
* Patients with adrenocortical dysfunction, chronic steroid users
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Respiratory adverse event
Timeframe: during gastric endoscopic submucosal dissection