CompletedNot Applicable

Is Lower Limb Neuromotor Control Diverse in Females With PF OA Contrasted With Asymptomatic Controls

Egypt42 participantsStarted 2022-06-30

Plain-language summary

Objective: to investigate whether females with PF OA descend stairs with different muscular recruitment strategies contrasted with similar aged healthy females. Methods: An observational comparative study will be conducted with thirty females with PF OA and 10 healthy ones. The onset times and electromyography (EMG) duration of multifidus, transversus abdominus (TrA), gluteus medius (GM), and vasti muscles will be measured by quantitative EMG during stair descent task. hypothesis: Investigators hypothesize that there won't be a significant difference between females with PF OA and their matched healthy group regarding the onset times and duration of vastus medialis obliqus (VMO), vastus lateralis (VL), gluteus medius (GM), multifidus, and transversus abdominus (TrA), during stair descent task.

Who can participate

Age range

35 Years – 55 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Anterior- or retro-patellar knee pain aggravated by at least two activities that load the PFJ (eg; stair ambulation, squatting and/or rising from sitting) .
. Pain during these activities presented on most days during the past month and their pain severity was ≥ 4 on an 11 point numerical pain scale during aggravating activities .,
. A grade less than (2) from postero-anterior views on the Kellgren - Lawrence (KL) grading scale.

Exclusion criteria

. concomitant pain from tibiofemoral joint or other knee structures . • Exclusion Criteria for Subjects from both groups:
. current or previous pain in the hip, lumbar spine or foot that lasted longer than 3 months and/or required intervention.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

The change of EMG onset of multifidus

Timeframe: from admission to discharge, up to two weeks

The change of EMG duration of multifidus

Timeframe: from admission to discharge, up to two weeks

The change of EMG duration of transversus abdominus

Timeframe: from admission to discharge, up to two weeks

The change of EMG onset of transversus abdominus

Timeframe: from admission to discharge, up to two weeks

The change of EMG onset of gluteus medius

Timeframe: from admission to discharge, up to two weeks

The change of EMG duration of gluteus medius

Timeframe: from admission to discharge, up to two weeks

The change of EMG onset of vastus medialis obliqus

Timeframe: from admission to discharge, up to two weeks

Trial details

NCT IDNCT05407077

SponsorCairo University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-12-13

View on ClinicalTrials.gov More Chondromalacia Patellae trials

Plain-language summary

Who can participate

Age range

35 Years – 55 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Anterior- or retro-patellar knee pain aggravated by at least two activities that load the PFJ (eg; stair ambulation, squatting and/or rising from sitting) .
. Pain during these activities presented on most days during the past month and their pain severity was ≥ 4 on an 11 point numerical pain scale during aggravating activities .,
. A grade less than (2) from postero-anterior views on the Kellgren - Lawrence (KL) grading scale.

Exclusion criteria

. concomitant pain from tibiofemoral joint or other knee structures . • Exclusion Criteria for Subjects from both groups:
. current or previous pain in the hip, lumbar spine or foot that lasted longer than 3 months and/or required intervention.

What they're measuring

The change of EMG onset of multifidus

Timeframe: from admission to discharge, up to two weeks

The change of EMG duration of multifidus

Timeframe: from admission to discharge, up to two weeks

The change of EMG duration of transversus abdominus

Timeframe: from admission to discharge, up to two weeks

The change of EMG onset of transversus abdominus

Timeframe: from admission to discharge, up to two weeks

The change of EMG onset of gluteus medius

Timeframe: from admission to discharge, up to two weeks

The change of EMG duration of gluteus medius

Timeframe: from admission to discharge, up to two weeks

The change of EMG onset of vastus medialis obliqus

Timeframe: from admission to discharge, up to two weeks