CompletedNot Applicable

Is Lower Limb Neuromotor Control Diverse in Females With PF OA Contrasted With Asymptomatic Controls

Egypt42 participantsStarted 2022-06-30

Plain-language summary

Objective: to investigate whether females with PF OA descend stairs with different muscular recruitment strategies contrasted with similar aged healthy females. Methods: An observational comparative study will be conducted with thirty females with PF OA and 10 healthy ones. The onset times and electromyography (EMG) duration of multifidus, transversus abdominus (TrA), gluteus medius (GM), and vasti muscles will be measured by quantitative EMG during stair descent task. hypothesis: Investigators hypothesize that there won't be a significant difference between females with PF OA and their matched healthy group regarding the onset times and duration of vastus medialis obliqus (VMO), vastus lateralis (VL), gluteus medius (GM), multifidus, and transversus abdominus (TrA), during stair descent task.

Who can participate

Age range35 Years – 55 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Anterior- or retro-patellar knee pain aggravated by at least two activities that load the PFJ (eg; stair ambulation, squatting and/or rising from sitting) .
✓. Pain during these activities presented on most days during the past month and their pain severity was ≥ 4 on an 11 point numerical pain scale during aggravating activities .,
✓. A grade less than (2) from postero-anterior views on the Kellgren - Lawrence (KL) grading scale.

Exclusion criteria

✕. concomitant pain from tibiofemoral joint or other knee structures . • Exclusion Criteria for Subjects from both groups:
✕. current or previous pain in the hip, lumbar spine or foot that lasted longer than 3 months and/or required intervention.
✕. a history of lower extremity, pelvis or spine fractures; spine, hip, knee or foot surgeries; hip or patellar subluxation/ dislocation.
✕. injury to any of knee ligaments or meniscus.
✕. systemic diseases (e.g. rheumatoid arthritis), neurological conditions or fibromyalgia . 5.The professional athletes; people who exercise more than two hours a day or every other day.

What they're measuring

The change of EMG onset of multifidus

Timeframe: from admission to discharge, up to two weeks

The change of EMG duration of multifidus

Timeframe: from admission to discharge, up to two weeks

The change of EMG duration of transversus abdominus

Timeframe: from admission to discharge, up to two weeks

The change of EMG onset of transversus abdominus

Timeframe: from admission to discharge, up to two weeks

The change of EMG onset of gluteus medius

Timeframe: from admission to discharge, up to two weeks

The change of EMG duration of gluteus medius

Timeframe: from admission to discharge, up to two weeks

The change of EMG onset of vastus medialis obliqus

Timeframe: from admission to discharge, up to two weeks

The change of EMG duration of vastus medialis obliqus

Trial details

NCT IDNCT05407077

SponsorCairo University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-12-13

View on ClinicalTrials.gov More Chondromalacia Patellae trials

Plain-language summary

Who can participate

Age range35 Years – 55 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Anterior- or retro-patellar knee pain aggravated by at least two activities that load the PFJ (eg; stair ambulation, squatting and/or rising from sitting) .
✓. Pain during these activities presented on most days during the past month and their pain severity was ≥ 4 on an 11 point numerical pain scale during aggravating activities .,
✓. A grade less than (2) from postero-anterior views on the Kellgren - Lawrence (KL) grading scale.

Exclusion criteria

✕. concomitant pain from tibiofemoral joint or other knee structures . • Exclusion Criteria for Subjects from both groups:
✕. current or previous pain in the hip, lumbar spine or foot that lasted longer than 3 months and/or required intervention.
✕. a history of lower extremity, pelvis or spine fractures; spine, hip, knee or foot surgeries; hip or patellar subluxation/ dislocation.
✕. injury to any of knee ligaments or meniscus.
✕. systemic diseases (e.g. rheumatoid arthritis), neurological conditions or fibromyalgia . 5.The professional athletes; people who exercise more than two hours a day or every other day.

What they're measuring

The change of EMG onset of multifidus

Timeframe: from admission to discharge, up to two weeks

The change of EMG duration of multifidus

Timeframe: from admission to discharge, up to two weeks

The change of EMG duration of transversus abdominus

Timeframe: from admission to discharge, up to two weeks

The change of EMG onset of transversus abdominus

Timeframe: from admission to discharge, up to two weeks

The change of EMG onset of gluteus medius

Timeframe: from admission to discharge, up to two weeks

The change of EMG duration of gluteus medius

Timeframe: from admission to discharge, up to two weeks

The change of EMG onset of vastus medialis obliqus

Timeframe: from admission to discharge, up to two weeks

The change of EMG duration of vastus medialis obliqus