Antibiotic Prophylaxis for TEVAR (NCT05405790) | Clinical Trial Compass
TerminatedNot Applicable
Antibiotic Prophylaxis for TEVAR
Stopped: Unable to enroll a sufficient number of patients
China457 participantsStarted 2022-01-01
Plain-language summary
The infection rate of thoracic endovascular aortic repair (TEVAR) is unknown due to a lack of epidemiological data. The rate currently available comes from researches conducted decades ago, when open surgery was the standard of care. Because of the potentially fatal consequences of a stent graft infection in the thoracic aorta, the investigators tend to prescribe antibiotic prophylaxis for at least three days. In this study, the investigators are going to collect data on patients receiving TEVAR in the past five years and provide the following information: a. the infection rate (MAGIC classification), b. the rate of fever, c. the results of the lab tests, such as the WBC count and C-reaction protein. d. risk factors associated with infection and fever.
Who can participate
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Diagnosed with thoracic aortic diseases
. Received TEVAR
Exclusion criteria
. Suspected infectious aortic disease, such as a mycotic aneurysm.
. TEVAR combined with open surgery
. Antibiotics have been used more than 24 hours before the operation
. Combined with immune deficiency disease or using hormone or immunosuppressant；
. The treatment is for the complications of TEVAR, such as endoleak
. Endovascular aortic repair for abdominal aortic disease
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Infection rate after TEVAR
Timeframe: during hospitalization (up to post-operation day 14)
2
Infection rate at one month after TEVAR
Timeframe: One month after TEVAR
3
Infection rate at six months after TEVAR
Timeframe: Six months after TEVAR
4
Infection rate at one year after TEVAR
Timeframe: One year after TEVAR
Trial details
NCT IDNCT05405790
SponsorFirst Affiliated Hospital of Zhejiang University