Platelet Transfusion Refractoriness is one of the severe complications after multiple transfusions in patients with severe thrombopenia. Platelet Transfusion Refractoriness is characterized by inefficient transfusion and arise from allo-antibodies specific of platelets antigenes, mostly carried by HLA-I molecules.
Age range
18 Years
Sex
ALL
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Research of predictive criteria of Platelet transfusion refractoriness
Timeframe: blood samples before the transfusion of each chemotherapy cycle