CompletedNot Applicable

Arthrogryposis Multiplex Congenita in Pediatric Age: Correlation Between MUScular MRI and Functional Evaluation

France97 participantsStarted 2022-05-01

Plain-language summary

The aim of our study is to evaluate the correlation between quantified fibro-adipous infiltration of muscles on MRI assessed by MERCURI Score and the functional abilities (deficiencies, activity limitations and social participation of pediatric patients with arthrogryposis.

Who can participate

Age range0 Years – 18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * age \< 18 at the first clinical evaluation or follow up exclusively in CHUGA pediatric rehabilitation unit * Clinical or molecular diagnosis of AMC established by geneticists at CHUGA * functional evaluation during consultation and follow-up in CHUGA pediatric rehabilitation unit * Muscle MRI of upper limbs, lower limbs and trunk performed at CHUGA pediatric radiology unit Exclusion Criteria: * Contra indication MRI. * MRI non exploitable. * Patient under guardianship or deprived of liberty

What they're measuring

Mercuri Scores of upper limbs, trunk, and lower limbs evaluated on muscle MRI T1

Timeframe: through study completion, an average of 1 year

Trial details

NCT IDNCT05393375

SponsorUniversity Hospital, Grenoble

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-06-01

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