Fully Closed-Loop Insulin Delivery in Abdominal Surgery (CLAB)

Inclusion Criteria: * Age 18 years or over * Pre-existing or anticipated (surgery-induced) diabetes other than type 1 diabetes * Expected to require insulin treatment in the perioperative period * Planned for elective major abdominal surgery at the University Hospital Bern or Basel expected to last ≥ 90 minutes, defined as colorectal, pancreatic, gastric (except bariatric surgery) and hepatic (≥ 2 segments) surgery Exclusion Criteria: * Physical or psychological condition likely to interfere with the normal conduct of the study and interpretation of the study results as judged by the investigator * Likely discharge earlier than 72 hours * Known or suspected allergy to insulin used in this clinical trial * Type 1 diabetes * Pregnancy, planned pregnancy, or breast feeding * Lack of safe contraception for female participants of childbearing potential for the entire study duration (medically reliable method of contraception are considered oral, injectable, or implantable contraceptives, intrauterine contraceptive devices, or any other methods judged as sufficiently reliable by the investigator in individual cases). * Medically documented allergy towards the adhesive (glue) of plasters or unable tolerate tape adhesive in the area of sensor placement * Serious skin diseases located at places of the body, which potentially are possible to be used for localisation of the glucose sensor * Illicit drug abuse or prescription drug abuse * Incapacity to give informed consent * Not will…