CompletedNot Applicable

Dental and Periodontal Changes Following the Acceleration of Alignment of Crowded Lower Anterior Teeth Using a Surgical Technique

Syria38 participantsStarted 2021-01-01

Plain-language summary

Patients at the Orthodontic Department of the University of Damascus Dental School will be examined and subjects who meet the inclusion criteria will be included. Then, initial diagnostic records (diagnostic gypsum models, internal and external oral photographs, and radiographic images) will be studied to ensure that the selection criteria are accurately matched. This study aims to compare two groups of patients with moderate crowding of the lower anterior teeth. Experimental group: the patients in this group will be treated with periodontally accelerated osteogenic orthodontics Control group: the patients in this group will be treated using fixed appliances without any acceleration method.

Who can participate

Age range

18 Years – 28 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * skeletal class I malocclusion (ANB=2-4) * normal vertical growth pattern. * moderate crowding of lower anterior teeth (i.e., 4-6 millimeters of a tooth size-arch length discrepancy) * 1 to 3 mm of overjet and 1 to 4 mm of the overbite * good oral health Exclusion Criteria: * medical, social, and psycho contraindications to oral surgery * presence of periodontal diseases * poor oral hygiene * previous orthodontic treatment

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in Little's Index of Irregularity

Timeframe: T0: one day before the beginning of treatment; T1: after 1 month; T2: after 2 months; T3: after 4 months; T4: after 5 months; T5: at the end of the alignment stage which is expected within 5 - 6 months

Change in the inter-canine width

Timeframe: T0: One day before the beginning of treatment; T1: at the end of the alignment stage

Change in the inter-2nd premolar width

Timeframe: T0: One day before the beginning of treatment; T1: at the end of the alignment stage

Trial details

NCT IDNCT05390320

SponsorDamascus University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-10-06

View on ClinicalTrials.gov More Crowding, Tooth trials

Plain-language summary

Who can participate

Age range

18 Years – 28 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change in Little's Index of Irregularity

Change in the inter-canine width

Timeframe: T0: One day before the beginning of treatment; T1: at the end of the alignment stage

Change in the inter-2nd premolar width

Timeframe: T0: One day before the beginning of treatment; T1: at the end of the alignment stage