Over the last 5 years, prostate embolization has developed as a treatment for symptomatic prostate adenoma. This long, complex procedure is effective in 80% of cases. Currently there are no means of better selecting patients to avoid this long procedure in non-responders. The hypothesis is that prostate perfusion parameters are correlated with the efficacy of embolization. Studying these prostate perfusion parameters in perfusion CT and evaluating prostate Iodine load in dual energy computed tomography will make it easier to select those patients who are most likely to respond.
Age range
18 Years
Sex
MALE
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A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Catheterized patients: Removal of the urinary catheter at 3 months
Timeframe: Month 3
Non-catheterized patients: 25% decrease in the International Prostate Symptom Score
Timeframe: Month 3
Non-catheterized patients: one point improvement in the Global Quality of Life Score.
Timeframe: Month 3
MRI perfusion parameters : Capillary permeability
Timeframe: 7 - 14 days before embolization
Scanner perfusion parameters : Capillary permeability
Timeframe: Day 0 (on the day of embolization)
MRI perfusion parameters : Extracellular volume
Timeframe: 7 - 14 days before embolization
Scanner perfusion parameters : Extracellular volume
Timeframe: Day 0 (on the day of embolization)
MRI perfusion parameters : Blood volume
Timeframe: 7 - 14 days before embolization
Scanner perfusion parameters : Blood volume
Timeframe: Day 0 (on the day of embolization)
MRI perfusion parameters : Maximum slope
Timeframe: 7 - 14 days before embolization
Scanner perfusion parameters : Maximum slope
Timeframe: Day 0 (on the day of embolization)
MRI perfusion parameters : Time to peak
Timeframe: 7 - 14 days before embolization
MRI perfusion parameters : Time to peak
Timeframe: Day 0 (on the day of embolization)
Scanner perfusion parameters : Prostate iodine load at 80 s.
Timeframe: 7 - 14 days before embolization
MRI perfusion parameters : Prostate iodine load at 80 s.
Timeframe: Day 0 (on the day of embolization)