UnknownNot Applicable

Injectable Platelet Rich Fibrin With Collagen Matrix in Treatment of Multiple Gingival Recession.

Iraq20 participantsStarted 2022-04-25

Plain-language summary

This study is proposing the use of i-PRF clot as a scaffold for the XCM in order to obtain a novel biomaterial, incorporating active growth factors and collagen matrix in a single framework, based on the potential effect of i-PRF to enhance fibroblast activity and angiogenesis stimulation for treatment of multiple gingival recession.

Who can participate

Age range

18 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Presence of at least two localized gingival recessions on either sides of the maxilla and/or mandible excluding molar region. * The cemento-enamel junction (CEJ) is visible in the teeth for root coverage procedures. * All recessions are type 1recession RT1 (cairo et al,2011) which correspond to Miller I\&II gingival recession * All patients must demonstrate adequate plaque control with a fullmouth plaque score less than 20% and with . * All patients at least 18 years of age and of both genders. Exclusion Criteria: * Smoker Patients . * Patients with diabetes. * Patients with a history of malignancy, radiotherapy, or chemotherapy for malignancy. * pregnant or nursing women. * Patients taking medications or having treatments with an effect on mucosal healing in general (e.g. steroids, large doses of antiinflammatory drugs). * Patients with a disease affecting connective tissue metabolism. * Patients allergic to collagen.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Reduction in gingival recession depth on the buccal sides of type one gingival recessionRT1

Timeframe: Between the baseline preoperative measurement and follow-up at 3 months and 6 months

Trial details

NCT IDNCT05389059

SponsorUniversity of Baghdad

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-03-30

View on ClinicalTrials.gov More Gingival Diseases trials