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The Effects of Individualized Lung-protective Ventilation With Lung Dynamic Compliance-guided Positive End-expiratory Pressure(PEEP) Titration on Postoperative Pulmonary Complications of Pediatric Video-assisted Thoracoscopic Surgery

China60 participantsStarted 2022-06-10

Plain-language summary

This study evaluates the influence of individualized lung-protective ventilation strategy(LPVS) on postoperative pulmonary complications(PPCs) through a randomized controlled trial when children undergoing thoracoscopic surgery with one-lung ventilation(OLV).The investigators evaluate the impact of using lung dynamic compliance-guided Positive End-expiratory Pressure(PEEP) versus conventional PEEP on a pressure-controlled ventilation(PCV).The researchers also analyzed perioperative vital signs and respiratory indicators of these LPVS.

Who can participate

Age range1 Month – 5 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Children undergoing elective thoracoscopic pulmonary surgery. * Written informed consent. * Children under 5 years old (including 5 years old) * ASA classification 1-2 * Respiratory Risk Assessment in Catalan Surgical Patients (ARISCAT) Criteria Low or Moderate Risk Exclusion Criteria: * Symptoms of upper respiratory tract infection or pulmonary infection in the past 4 weeks, chest X-ray suggests pneumonia * Severe circulatory disease * Children with bullae * Intraoperative arterial blood pressure monitoring cannot be performed * Respiratory Risk Assessment in Catalan Surgical Patients (ARISCAT) Criteria Rated High Risk

What they're measuring

Postoperative pulmonary complication(PPCs) rate at 7 days

Timeframe: 7 days after surgery

Trial details

NCT IDNCT05386901

SponsorJiaxiang Chen

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-06-01

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