CompletedNot Applicable

Formulated PSTA Injection Versus PATA Alone in the Management of Macular Edema Secondary to Non-ischemic Retinal Vein Occlusions

Egypt78 participantsStarted 2020-01-02

Plain-language summary

The aim of this study is to compare formulated Posterior Subtenon Triamcinolone acetonide (PSTA) injection versus Posterior Subtenon Triamcinolone acetonide alone in the management of macular edema secondary to non-ischemic retinal vein occlusions, either central or branch.

Who can participate

Age range

40 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diminution vision due to macular edema secondary to non-ischemic retinal vein occlusions, either central or branch, as evidenced by clinical and angiographic evaluation * CMT ≥ 250 µ. * Willing to participate in the study Exclusion Criteria: * Unwilling to participate in the study. * Ischemic RVO * Prior laser treatment * Glaucoma/Ocular Hypertension * Cataract which lead to difficulty in the evaluation of macula * Vitreous hemorrhage * Macular ischemia * Iris neovascularisation * patients with intravitreal injection of anti VEGFs, steroid, or any intraocular surgery 3 months prior to the inclusion.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Best-corrected visual acuity (BCVA)

Timeframe: Baseline

Best-corrected visual acuity (BCVA)

Timeframe: at 1st month

Best-corrected visual acuity (BCVA)

Timeframe: at 3rd month

Best-corrected visual acuity (BCVA)

Timeframe: at 6th month

central macular thickness ( CMT)

Timeframe: at baseline

central macular thickness ( CMT)

Timeframe: at 1st month

central macular thickness ( CMT)

Timeframe: at 3rd month

central macular thickness ( CMT)

Timeframe: at 6th month

Trial details

NCT IDNCT05385562

SponsorAl-Azhar University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-05-01

View on ClinicalTrials.gov More Macula Edema trials

Who can participate

Age range

40 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Best-corrected visual acuity (BCVA)

Timeframe: Baseline

Best-corrected visual acuity (BCVA)

Timeframe: at 1st month

Best-corrected visual acuity (BCVA)

Timeframe: at 3rd month

Best-corrected visual acuity (BCVA)

Timeframe: at 6th month

central macular thickness ( CMT)

Timeframe: at baseline

central macular thickness ( CMT)

Timeframe: at 1st month

central macular thickness ( CMT)

Timeframe: at 3rd month

central macular thickness ( CMT)

Timeframe: at 6th month