UnknownNot Applicable

To Compare the Outcome of Temporary Portocaval Shunt During Recipient Hepatectomy Versus No Shunt in Adult Elective Live Donor Liver Transplantation.

40 participantsStarted 2022-05-25

Plain-language summary

Temporary portocaval Shunt during recipient hepatectomy improves intra operative parameters and morbidity in LDLT recipients

Who can participate

Age range

18 Years – 75 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Exclusion criteria

. Acute Liver Failure as an indication for transplant
. Pediatric transplants
. Presence of Yerdel grade III and grade IV Portal vein thrombosis
. Presence of significant portosystemic shunting (greater than 10mm) in pre operative period.
. Patients who have undergone TIPS procedure.
. Hypercoagulable states like Budd-Chiari syndrome
. Refusal to participate in the study

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Blood Pressure between two groups at fixed time points

Timeframe: T0- At the beginning of the procedure

Ionotropes requirement between two groups at fixed time points

Timeframe: T0- At the beginning of the procedure

Lactate level between two groups at fixed time points

Timeframe: T0- At the beginning of the procedure

Blood Pressure between two groups at fixed time points

Timeframe: T1- During procedure- Before portocaval shunt formation

Ionotropes requirement between two groups at fixed time points

Timeframe: T1- During procedure- Before portocaval shunt formation

Lactate level between two groups at fixed time points

Timeframe: T1- During procedure- Before portocaval shunt formation

Blood Pressure between two groups at fixed time points

Timeframe: T2- During procedure- Just Before Reperfusion of graft liver

Trial details

NCT IDNCT05385120

SponsorInstitute of Liver and Biliary Sciences, India

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-07-30

Contact for this trial

Manoj Kumar YL, MBBS, MS

9164313430 manojkumaryl91@gmail.com

View on ClinicalTrials.gov More Portosystemic Shunt trials

Who can participate

Age range

18 Years – 75 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Exclusion criteria

. Acute Liver Failure as an indication for transplant
. Pediatric transplants
. Presence of Yerdel grade III and grade IV Portal vein thrombosis
. Presence of significant portosystemic shunting (greater than 10mm) in pre operative period.
. Patients who have undergone TIPS procedure.
. Hypercoagulable states like Budd-Chiari syndrome
. Refusal to participate in the study

What they're measuring

Blood Pressure between two groups at fixed time points

Timeframe: T0- At the beginning of the procedure

Ionotropes requirement between two groups at fixed time points

Timeframe: T0- At the beginning of the procedure

Lactate level between two groups at fixed time points

Timeframe: T0- At the beginning of the procedure

Blood Pressure between two groups at fixed time points

Timeframe: T1- During procedure- Before portocaval shunt formation

Ionotropes requirement between two groups at fixed time points

Timeframe: T1- During procedure- Before portocaval shunt formation

Lactate level between two groups at fixed time points

Timeframe: T1- During procedure- Before portocaval shunt formation

Blood Pressure between two groups at fixed time points

Timeframe: T2- During procedure- Just Before Reperfusion of graft liver