CompletedNot Applicable

Outcome of Root Canal Treatments Obturated With Calcium Silicate Based Sealers

Italy109 participantsStarted 2019-02-01

Plain-language summary

The clinical use of a flowable premixed calcium-silicate bioceramic sealer used in association with warm carrier-based/single-cone technique will be compared with epoxy resin-based sealer with carrier-based technique.

Who can participate

Age range

18 Years – 75 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. age 18-75 years
. no use of antiresorptive or antiangiogenic drug
. healthy status (ASA 1 or 2).
. Needing one or more root canal treatment

Exclusion criteria

. Teeth with less than 2 walls of structural integrity
. Wide apexes (\>40 diameter)
. ASA \> 3,
. Any pathology that could compromise bone healing or the immune response,
. pregnancy or breast feeding
. heavy smoking (\>15 cigarettes/day), (Tverdal \& Bjartveit 2006)
. exposure to radiation therapy focussed on the head and neck region and malignant disease directly involving the jaws.
. Lacks of occlusal contacts

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Healing rate

Timeframe: 24 months

Trial details

NCT IDNCT05376033

SponsorUniversity of Bologna

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-02-01

View on ClinicalTrials.gov More Endodontically Treated Teeth trials