Infertility is a disease that seriously affects the physical and mental health of women of childbearing age. The incidence of infertility has been increasing in recent years. Studies have shown that the occurrence of infertility may be related to environmental endocrine disrupting substances. This project was designed to establish a cohort study on environmental endocrine disrupting substances and in vitro fertilization (IVF) treatment, collect blood, urine, semen, follicular fluid, granulosa cells, chorionic decidua biological specimens, and then follow up on the pregnancy outcomes. The concentration of disrupting substances was detected and then found the associations between environmental endocrine disrupting substances and female reproductive health.
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Number of eggs retrieved
Timeframe: immediately after the eggs retrieved
the number of available embryos
Timeframe: 1 week after the eggs retrieved
the clinical pregnancy rate
Timeframe: 4 weeks after the embryos transfer
the miscarriage rate
Timeframe: 7 months after embryos transfer
the live birth rate
Timeframe: 40 weeks after embryos transfer