Active — Not RecruitingNot Applicable

Multicenter Registry of Coronary Flow-Derived Indexes for Coronary Microvascular Disease (Multicenter FLOW-CMD Registry)

South Korea1,003 participantsStarted 2022-04-22

Plain-language summary

Multicenter FLOW-CMD registry is a prospective, multi-center, registry study. The aim of the study is to evaluate prognostic implications of coronary microvascular disease (CMD) in patients with ischemic heart disease (IHD) undergoing revascularization decision using FFR or other non-hyperemic pressure ratios.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Subject must be ≥18 years
✓. Patients suspected with IHD
✓. Patients undergoing physiologic assessment (CFR, IMR, and FFR) for evaluation of severity of CAD
✓. Subject is able to verbally confirm understandings of risks, benefits and treatment alternatives of receiving invasive physiologic or imaging evaluation and he/she or his/her legally authorized representative provides written informed consent to any study related procedure.

Exclusion criteria

✕. Cardiogenic shock (systolic blood pressure \<90mmHg or requiring inotropics to maintain blood pressure \>90mmHg) or cardiac arrest
✕. Non-cardiac co-morbid conditions are present with life expectancy \<2 year (per site investigator's medical judgment).
✕. Inability to undergo physiologic assessment (CFR, IMR, and FFR)
✕. Pregnant or lactating women

What they're measuring

Patient-oriented composite outcomes (POCO)

Timeframe: 1 year after last patient enrollment

Trial details

NCT IDNCT05369182

SponsorSamsung Medical Center

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-12-31

View on ClinicalTrials.gov More Coronary Microvascular Disease trials