CompletedNot Applicable

Relationship Between Right Atrial Volume Index, Functional Capacity and Inflammatory Biomarkers in Patients With COPD.

Egypt151 participantsStarted 2022-01-19

Plain-language summary

Right ventricular (RV) dysfunction is associated with increased morbidity and mortality in patients with chronic obstructive pulmonary disease (COPD). Assessment of RV function by echocardiography is challenging. Easy visualization of the right atrium (RA) by echocardiography , allows quantitative, highly reproducible assessment of RA volume. The aim of the present study is to evaluate the relationship between the right atrial volume index (RAVI) and functional capacity in patients with COPD , quantified by the COPD assessment test (CAT) questionnaire as an early predictor of right heart affection.

Who can participate

Age range18 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria - Patients included were \> 18 years old of both sexes and left ventricular ejection fraction (LVEF) \>55%.The following clinical and demographic parameters were recorded; age, sex, Current cigarette smoking was defined as active smoking within the past 12 months. Coronary artery disease was obtained by history or previous medical records. Exclusion criteria \- Patients with diagnosis of other respiratory diseases (e.g. asthma, interstitial pulmonary fibrosis , tuberculosis or lung cancer ), ischemic heart disease, congestive heart failure, valvular heart disease and congenital heart diseases, were excluded. Other chronic diseases, such as kidney or liver failure and cancer were also excluded.

What they're measuring

RAVI (ml/m2)

Timeframe: 3 month

Adiponectin (mg/L)

Timeframe: 3 month

Neopterin (nmol/L)

Timeframe: 3 month

IL-1beta (pg/mL)

Timeframe: 3 month

Trial details

NCT IDNCT05366400

SponsorDamanhour University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-08-30

View on ClinicalTrials.gov More COPD trials

Plain-language summary

Who can participate

Age range18 Years – 60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.