RecruitingNot Applicable

Selective CT for Anticoagulated Head Injured Patients

Canada4,000 participantsStarted 2022-02-01

Plain-language summary

The goal is to derive and a clinical decision rule for safe exclusion of traumatic brain injury without neuroimaging in head-injured ED patients who take anticoagulant medications. The objectives are to: 1. Derive and externally validate a new highly sensitive and maximally specific clinical decision rule for the exclusion of traumatic brain injury in head-injured ED patients who take anticoagulant medications; and, 2. Estimate the sensitivity and specificity of existing head injury clinical decision rules in head-injured ED patients who take anticoagulant medications.

Who can participate

Age range16 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age ≥16 years * Presents to the emergency department after a head injury * Patient has a head CT in the emergency department * Is a current anticoagulant user Exclusion Criteria: * Head injury occurred \>48 h before patient's arrival to the emergency department * Penetrating head injury * Previously enrolled * Patient resides outside of the hospital's catchment area * Patient was transferred from another emergency department following neuroimaging * Patient was not managed by the emergency or trauma physician in the emergency department * Leaves the emergency department prior to completion of their medical assessment

What they're measuring

Clinically important traumatic brain injury

Timeframe: Index emergency department presentation

Trial details

NCT IDNCT05364749

SponsorDr. Kerstin de Wit

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-03-15

Contact for this trial

Natasha Clayton, CRA, RA

416-566-3590 natasha.clayton@queensu.ca

View on ClinicalTrials.gov More Head Injury trials