Interest of Immersive Virtual Reality on Stress During Botulinum Toxin Injections in Spasticity (RVTOX)

Inclusion Criteria: * Adult patient, male or female, suffering from spasticity of neurological origin (multiple sclerosis, stroke, head trauma, etc.) and eligible for treatment by botulinum toxin injection * Able to give an informed consent to participate in research * Affiliation to Social Security. Exclusion Criteria: * Contraindication to virtual reality (epilepsy, schizophrenia, strabismus, amblyopia, anisometropia, local contraindication to wearing a helmet (lesion of the face or the skull) * Major cognitive disorders * Any medical condition deemed by the investigator to be incompatible with the research. * Indication of sedation by MEOPA during botulinum toxin injection sessions. * Patients who have already experienced virtual reality * Drug treatment or medical condition that may affect heart rate variability * Pregnant or breastfeeding women * Patients under safeguard of justice * Refusal of participation.