CompletedNot Applicable

Incorporation of Vitamin K Into Uremic Lipoproteins

Germany20 participantsStarted 2020-03-31

Plain-language summary

Chronic kidney disease (CKD) patients have an increased cardiovascular risk with corresponding cardiovascular calcifications. CKD patients exhibit a functional vitamin K deficiency. Calcification can be prevented by vitamin K intake. The aim of this study is to investigate the cause for the vitamin K deficiency beyond a diminished dietary vitamin K uptake.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria * Age ≥ 18 years * Controls: adequate kidney function (GFR \> 60 ml/min/1,73m2) * Patients: chronic haemodialysis * Written consent to take part in the study Exclusion criteria * Intake of vitamin K antagonists * gastro-intestinal diseases interfering with vitamin K intake * profound anemia with an Hb \< 10 g/dl * judicial or official commitment to an institution * pregnancy and lactation

What they're measuring

Vitamin K content in lipoproteins

Timeframe: 1 year

Trial details

NCT IDNCT05360342

SponsorRWTH Aachen University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-07-15

View on ClinicalTrials.gov More Vitamin K Deficiency trials