UnknownNot Applicable

Cesarean Section Scar Niche: The Impact on ART Outcome

Egypt266 participantsStarted 2022-05-25

Plain-language summary

To evaluate the impact of the presence of cesarean section niche and its characteristics on the outcome of ART cycles.

Who can participate

Age range

18 Years – 37 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Aged from 18 - 37 years old.
. Having a history of one or more previous CS with ultrasonographic visible cesarean section niche (for the group with cs scar niche), which is regarding to European Niche Taskforce is an indentation of the uterine myometrium of at least 2 mm at the site of the CS scar (Jordans et al., 2019).
. A normal uterus with no anomalies or pathologies.
. At least one good-quality embryo available for transfer.

Exclusion criteria

. Younger than 18 or older than 37 years old.
. Congenital uterine abnormality or pathology.
. Presence of a hydrosalpinx.
. ICSI cycles with TESE samples.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

The effect of cesarean scar niche and its characteristics on ongoing pregnancy rate of ART cycles.

Timeframe: 3 months

Trial details

NCT IDNCT05358678

SponsorRahem Fertility Center

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-05

Contact for this trial

Rana nabil, MSc

01005899460 rananabil51@gmail.com

View on ClinicalTrials.gov More Cesarean Section trials