Active — Not RecruitingNot Applicable

Anorexia Nervosa and Its Effects on Brain Function, Body Metabolism and Their Interaction in Adolescents

Finland33 participantsStarted 2022-01-01

Plain-language summary

The aim of the research project is to investigate the neurological, physiological and behavioral underpinnings associated with the development of anorexia nervosa in adolescents. The goal of the project is to enable new ways to both predict the course of the disease and to influence this process.

Who can participate

Age range13 Years – 17 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria for anorexia nervosa patients: * Female sex * Age 13-17 years * Body mass index \< 17.5 kg/m2 * Currently fulfilling modified Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) diagnosis criteria for anorexia nervosa with or without amenorrhea * Anorexia nervosa diagnosed within 2 yers Inclusion criteria for healthy controls: * Female sex * Age 13-17 years * Body mass index 18,5-25 kg/m2 * No lifetime history of obesity (Body mass index ≥ 30) or eating disorders Exclusion criteria: * Any chronic illness or medication that could affect glucose metabolism or neurotransmission * Any other current mental disorder (excluding anorexia nervosa for the patient participants) * Severe previous mental disorder (excluding anorexia nervosa for the patient participants) * Smoking of tobacco, snuffing, or use of narcotics * Abusive use of alcohol

What they're measuring

Changes in brain reward system and metabolism in anorexia nervosa patients

Timeframe: 3 years

Trial details

NCT IDNCT05357053

SponsorTurku University Hospital

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2024-12-31

View on ClinicalTrials.gov More Anorexia Nervosa trials