CompletedNot Applicable

Effects of Yoga on Sodium-induced Pressor Responses in African American Adults

United States15 participantsStarted 2021-09-01

Plain-language summary

This investigation aims to determine the effects of a 4-week yoga intervention on sodium-induced pressor and endothelial function responses as well as markers of renal sodium handling in African American adults.

Who can participate

Age range

18 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * African American * Adults ages 18-60 years Exclusion Criteria: * pregnancy or within 60 days postpartum * having taken blood pressure (including diuretics beta-blockers, ACE inhibitors, angiotensin receptor blockers, and calcium channel blockers) or statin medications within the past 3 months (statins have been demonstrated to reduce oxidative stress which could impact flow-mediated dilation); * infection (viral or other) within the past 4 weeks; * having adrenal or endocrine tumors (these could impact BP); * renal disease defined as a glomerular filtration rate (GFR) of less than 60 (creatinine will be tested at initial screening and GFR will be calculated); * prior myocardial infarction; vii) known coronary heart disease; * personal history of stroke; * heart failure; * cardiac arrhythmias; * chronic obstructive pulmonary disease; * recent chest pain or dyspnea; * orthopedic limitations that preclude the execution of yoga postures; * current insulin dependence; * currently taking steroid medications; * currently undergoing chemotherapy or radiation; * having practiced yoga or yogic breathing techniques at least once weekly consistently within the past 3 months; * heat intolerance or electrolyte imbalances (hypo- or hyper-natremia or hypo- or hyper-kalemia).

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in blood pressure from low- to high-sodium dietary conditions

Timeframe: Measurements will be completed after 3 days of low and 3 days of high sodium intake at baseline and after 4 weeks for both conditions.

Change in endothelial function from low- to high-sodium dietary conditions.

Timeframe: Measurements will be completed after 3 days of low- and 3 days of high-sodium intake at baseline and at week 4.

Change in arterial stiffness from low- to high-sodium dietary conditions.

Timeframe: Measurements will be completed after 3 days of low- and 3 days of high-sodium intake at baseline and at week 4.

Trial details

NCT IDNCT05353270

SponsorTexas State University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-07-01

View on ClinicalTrials.gov More Blood Pressure trials

Who can participate

Age range

18 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change in blood pressure from low- to high-sodium dietary conditions

Timeframe: Measurements will be completed after 3 days of low and 3 days of high sodium intake at baseline and after 4 weeks for both conditions.

Change in endothelial function from low- to high-sodium dietary conditions.

Timeframe: Measurements will be completed after 3 days of low- and 3 days of high-sodium intake at baseline and at week 4.

Change in arterial stiffness from low- to high-sodium dietary conditions.

Timeframe: Measurements will be completed after 3 days of low- and 3 days of high-sodium intake at baseline and at week 4.