CompletedNot Applicable

Effects of Yoga on Sodium-induced Pressor Responses in African American Adults

United States15 participantsStarted 2021-09-01

Plain-language summary

This investigation aims to determine the effects of a 4-week yoga intervention on sodium-induced pressor and endothelial function responses as well as markers of renal sodium handling in African American adults.

Who can participate

Age range18 Years – 60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * African American * Adults ages 18-60 years Exclusion Criteria: * pregnancy or within 60 days postpartum * having taken blood pressure (including diuretics beta-blockers, ACE inhibitors, angiotensin receptor blockers, and calcium channel blockers) or statin medications within the past 3 months (statins have been demonstrated to reduce oxidative stress which could impact flow-mediated dilation); * infection (viral or other) within the past 4 weeks; * having adrenal or endocrine tumors (these could impact BP); * renal disease defined as a glomerular filtration rate (GFR) of less than 60 (creatinine will be tested at initial screening and GFR will be calculated); * prior myocardial infarction; vii) known coronary heart disease; * personal history of stroke; * heart failure; * cardiac arrhythmias; * chronic obstructive pulmonary disease; * recent chest pain or dyspnea; * orthopedic limitations that preclude the execution of yoga postures; * current insulin dependence; * currently taking steroid medications; * currently undergoing chemotherapy or radiation; * having practiced yoga or yogic breathing techniques at least once weekly consistently within the past 3 months; * heat intolerance or electrolyte imbalances (hypo- or hyper-natremia or hypo- or hyper-kalemia).

What they're measuring

Change in blood pressure from low- to high-sodium dietary conditions

Timeframe: Measurements will be completed after 3 days of low and 3 days of high sodium intake at baseline and after 4 weeks for both conditions.

Change in endothelial function from low- to high-sodium dietary conditions.

Timeframe: Measurements will be completed after 3 days of low- and 3 days of high-sodium intake at baseline and at week 4.

Change in arterial stiffness from low- to high-sodium dietary conditions.

Timeframe: Measurements will be completed after 3 days of low- and 3 days of high-sodium intake at baseline and at week 4.

Trial details

NCT IDNCT05353270

SponsorTexas State University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-07-01

View on ClinicalTrials.gov More Blood Pressure trials

Who can participate

Age range18 Years – 60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change in blood pressure from low- to high-sodium dietary conditions

Timeframe: Measurements will be completed after 3 days of low and 3 days of high sodium intake at baseline and after 4 weeks for both conditions.

Change in endothelial function from low- to high-sodium dietary conditions.

Timeframe: Measurements will be completed after 3 days of low- and 3 days of high-sodium intake at baseline and at week 4.

Change in arterial stiffness from low- to high-sodium dietary conditions.

Timeframe: Measurements will be completed after 3 days of low- and 3 days of high-sodium intake at baseline and at week 4.