STOPS Trial: Total vs Subtotal Colectomy for Slow Transit Constipation (NCT05352074) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
STOPS Trial: Total vs Subtotal Colectomy for Slow Transit Constipation
China252 participantsStarted 2022-03-27
Plain-language summary
Total colectomy with ileorectal anastomosis is a traditional surgical option for slow transit constipation (STC). Subtotal colectomy with caecorectal anastomosis have been reported to be a potential alternative approach. Thus, the optimal surgical option for STC is controversial.
Who can participate
Age range18 Years – 80 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Patients (≥18 years of age) of either sex
✓. Patients with conditions in agreement with the Roman IV criteria of functional constipation
✓. Patients have less than one complete spontaneous bowel movement per week
✓. Patients rely on laxatives to assist defecation for a long time
✓. More than 20% the radio-paque markers localized in the colon after 72 hours based on colonic transit studies
✓. Patients were refractory to conservative treatment for more than 1 year
✓. Patients with a strong desire for surgery
Exclusion criteria
✕. Pregnant or breast-feeding women
✕. Patients with megacolon, megarectum,severe spastic constipation, severe rectocele, rectal prolapse (Oxford Grade IV or above)
✕. Patients with colorectal neoplasms
✕. Patients with small intestinal slow transit
✕. Patients with constipation-predominant irritable bowel syndrome
✕. Patients with inflammatory bowel disease
✕. Patients with ileostomy
What they're measuring
1
Wexner Constipation Score
Timeframe: From the pre-operation to 36 months following surgery