CompletedNot Applicable

Pain Reduction in Maxillomandibular Surgery Using Maxillary and Mandibular Nerve Blocks

France50 participantsStarted 2022-05-23

Plain-language summary

Maxillo-mandibular osteotomy is a painful surgery which requires mostly opioids use. Recent studies on maxillary and mandibular nerve blocks have suggested benefit in maxillo-facial surgery but have been poorly investigated in orthognathic surgery. This study is designed to evaluate analgesic effectiveness, through opioids consumption, of a bilateral double ultra-sound guided nerve blocks (maxillar and mandibular nerve) in maxillo-mandibular osteotomy.

Who can participate

Age range

15 Years – 45 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients from 15 to 45 years old, * Scheduled for maxillary-mandibular osteotomy, * Registered in French social insurance register, * With informed consent disclosure. Exclusion Criteria: * American Society of Anesthesiologists (ASA) classification ≥ 3 * Innate or acquired hemostasis pathology, * Peripheric neuropathy, * Drug intake for chronic pain, * Infection/scar at needle insertion site, * Associated rhinoplasty surgery, * Allergy to local anesthetics, * Pregnant woman or potentially, * Breastfeeding woman, * Already registered in other clinical trial, * Adults under legal protection of incapable adult, * Cognitive disease impairing using of evaluation tools performed in protocol, * All contraindication of anesthetics drugs used in protocol.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

The opioid consumption (in Morphine Milligram Equivalents) after the first 24 hours post-surgery.

Timeframe: 24 hours post-surgery

Trial details

NCT IDNCT05351151

SponsorUniversity Hospital, Toulouse

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-03-29

View on ClinicalTrials.gov More Pain, Post Operative trials