Active — Not RecruitingNot Applicable

Intercostal Nerve Cryotherapy in Patients Undergoing Minimally Invasive Pulmonary Resection

United States110 participantsStarted 2022-04-21

Plain-language summary

This is a research study designed to test whether a treatment called Intercostal Nerve Cryotherapy is an effective way to help control post-surgical pain for patients undergoing minimally invasive pulmonary resection. There are two treatment groups in this study, a cryotherapy group and control group. Cryotherapy is a method of controlling pain by freezing nerves between the ribs that would transmit pain impulses to the brain.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Patients 18 year and older.
✓. Undergoing elective minimally invasive (VATS or robotic) lung resection for nodules (wedge resection, segmentectomy, lobectomy).
✓. Performance status of 1 or 2.

Exclusion criteria

✕. Patients with ejection fraction less than 40%
✕. Patients with creatinine greater than 1.5.
✕. Patients with Child's B or C cirrhosis
✕. Patients on chronic narcotics for other reasons
✕. Patients diagnosed with fibromyalgia
✕. Patients who had previous thoracic surgery on the same side.
✕. Patients who cannot communicate in English.
✕. Patients unable to provide informed consent for the study.

What they're measuring

Total morphine dose

Timeframe: to discharge (up to 14 days)

Pain control

Timeframe: to discharge (up to 14 days)

Trial details

NCT IDNCT05348447

SponsorAllegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-03-20

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