Frequency of Hyperparathyroidism in Postmenopausal Osteoporosis and Its Treatment (NCT05347082) | Clinical Trial Compass
CompletedNot Applicable
Frequency of Hyperparathyroidism in Postmenopausal Osteoporosis and Its Treatment
Mexico47 participantsStarted 2021-04-29
Plain-language summary
Recently, an increase in the prevalence of hyperparathyroidism and hypovitaminosis D in postmenopause women has been occurring in Mexico and the world. Chronic exposure to the parathyroid hormone (PTH) is catabolic for the bone, worsening the state of osteoporosis. However, it is unclear whether these conditions could significantly improve bone mineral density (BMD). In the present work, it was shown that the resolution of hyperparathyroidism in postmenopausal women improves osteoporosis.
Who can participate
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Acceptance to participate in the study with informed consent.
* Postmenopausal osteoporosis or osteopenia.
* Primary or secondary hyperparathyroidism.
* Insufficiency or deficiency of vitamin D.
* Multi-treated postmenopausal osteoporosis.
* Postmenopausal osteoporosis without treatment.
Exclusion Criteria:
* Different osteoporosis aetiology not related to oestrogenic deficiency.
* Thyroid pathology.
* Previous treatment with vitamin D, thiazide diuretics, lithium, Teriparatide or glucocorticoids.
* Known allergies to vitamin D.
* Addison's disease, pheochromocytoma, and depressive disorders.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Number of Participants with Remission of Hyperparathyroidism
Timeframe: 4 weeks
2
Number of Participants with Remission of Hypovitaminosis D
Timeframe: 4 weeks.
3
Change from baseline hip T score at 4 weeks
Timeframe: 4 weeks
4
Change from baseline lumbar spine T score at 4 weeks