CompletedPhase 2

Sertraline Effect in Uremic Pruritis

Egypt60 participantsStarted 2022-05-01

Plain-language summary

This study aims to assess the effect of sertraline on uremic pruritis in patients undergoing regular haemodialysis.

Age range18 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✕. Primary skin diseases (eczema, psoriasis, allergic dermatitis or drug rash).
✕. Peripheral neuropathy, thyroid disease, leukemia, lymphoma, liver disease, Systemic lupus erythematosus or pregnancy.
✕. Patients who consumed emollients cream, antihistamine, opioid antagonist, immunosuppressants, cholestyramine, corticosteroids or UVB phototherapy 1 month before study.
✕. calcium X phosphorus (Ca X P) \>55.0 mg/dl, P \>5.5 mg/dl, parathyroid hormone (PTH) \>450 pg/ml.
✕. Selective serotonin reuptake inhibitors intolerance.

change in uremic pruritis intensity

Timeframe: 8 weeks

NCT IDNCT05341843

SponsorAlexandria University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-09-01