CompletedNot Applicable

Prophylactic Cerclage for Twin Pregnancy With Shortened Cervix

Egypt100 participantsStarted 2021-12-20

Plain-language summary

This randomized controlled trial is aimed to evaluate pregnancy and neonatal outcomes in twin pregnancies, in which a cervical cerclage is placed due to the shortening of the cervix with or without visible fetal membranes.

Who can participate

Age range18 Years – 45 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age between 18-45 years. * Dichorionic twins. * Transvaginal sonographic cervical length is \<25 mm with or without internal os dilatation ≥10 mm at 14-20 weeks gestational age. * Asymptomatic. Exclusion Criteria: * Triplets and quadruplets. * Monochorionic twins. * Threatened/ inevitable miscarriage * Bulging membranes through the external os. * Extremes of age. * Major fetal anomalies. * Known cases with uterine anomalies e.g. bicornuate uterus, uterus didelphis… etc. * Fetal demise. * Fetal reduction in the current pregnancy.

What they're measuring

The incidence of preterm birth at ≤33+6, and ≤31+6 weeks with cervical length ≤25 mm

Timeframe: Immediate reporting of cases at time of delivery through study completion, an average of 1 year

Trial details

NCT IDNCT05338164

SponsorZagazig University

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2024-08-27

View on ClinicalTrials.gov More Preterm Birth trials