The proposed clinical trial would evaluate the use of smartphone applications ("apps", which have well-established efficacy in reducing cigarette and alcohol use) to prevent relapse among patients receiving medication-assisted treatment for opioid use disorder. In addition to standard app-based self-monitoring of drug use and personalized feedback, project innovation is enhanced by the proposed use of location-tracking technology for targeted, personalized intervention when participants enter self-identified areas of high risk for relapse. Furthermore, the proposed sub-study would use longitudinal functional neuroimaging to elucidate the brain-cognition relationships underlying individual differences in treatment outcomes, offering broad significance for understanding and enhancing the efficacy of this and other app-based interventions.
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Urinalysis - Week 0 (Intake)
Timeframe: 1 day
Urinalysis - Week 1
Timeframe: 1 week
Urinalysis - Week 2
Timeframe: 2 weeks
Urinalysis - Week 3
Timeframe: 3 weeks
Urinalysis - Week 4
Timeframe: 4 weeks
Urinalysis - Week 5
Timeframe: 5 weeks
Urinalysis - Week 6
Timeframe: 6 weeks
Urinalysis - Week 7
Timeframe: 7 weeks
Urinalysis - Week 8
Timeframe: 8 weeks
Urinalysis - Week 9
Timeframe: 9 weeks
Urinalysis - Week 10
Timeframe: 10 weeks
Urinalysis - Week 11
Timeframe: 11 weeks
Urinalysis - Week 12
Timeframe: 12 weeks
Urinalysis - Week 13
Timeframe: 13 weeks
Urinalysis - Week 14
Timeframe: 14 weeks
Urinalysis - Week 15
Timeframe: 15 weeks
Urinalysis - Week 16
Timeframe: 16 weeks
Urinalysis - Week 17
Timeframe: 17 weeks
Urinalysis - Week 18
Timeframe: 18 weeks
Urinalysis - Week 19
Timeframe: 19 weeks
Urinalysis - Week 20
Timeframe: 20 weeks
Urinalysis - Week 21
Timeframe: 21 weeks
Urinalysis - Week 22
Timeframe: 22 weeks
Urinalysis - Week 23
Timeframe: 23 weeks
Urinalysis - Week 24
Timeframe: 24 weeks
Urinalysis - Week 25
Timeframe: 25 weeks
Urinalysis - Week 26
Timeframe: 26 weeks