TerminatedNot Applicable

Aqueous Biomarker Levels in Diabetic Retinopathy and Diabetic Macular Edema

Stopped: Dissolution of the ophthalmology department

United States107 participantsStarted 2022-02-10

Plain-language summary

The DRAGONS study is a non-interventional, prospective study that will 1. characterize disease state biomarker (including cytokines, KKS metabolites, and cell adhesion molecules) levels from aqueous humor of subjects with various stages of diabetic retinopathy (DR) and diabetic macular edema (DME) as well as other retinal pathologies, and 2. correlate a broad array of aqueous humor disease state biomarkers with DR severity, DME anti-vascular endothelial growth factor (VEGF) responsiveness, and other retinal pathologies.

Who can participate

Age range18 Years

SexALL

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Exclusion criteria

✕. Prior intraocular or subtenon steroid injection in the study eye within the prior 1 year of signing informed consent;
✕. Prior focal or grid laser photocoagulation in the study eye if within 90 days of signing informed consent;
✕. Prior panretinal photocoagulation in the study eye if within 90 days of signing informed consent;
✕. Intraocular or refractive surgery in the study eye within 90 days of signing informed consent;
✕. Systemic anti-VEGF treatment within 90 days of signing informed consent

What they're measuring

Aqueous Humor Levels of Disease State Biomarkers

Timeframe: Baseline

Trial details

NCT IDNCT05333055

SponsorGreater Houston Retina Research

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-05-15

View on ClinicalTrials.gov More Diabetic Retinopathy trials