CompletedNot Applicable

Lactobacillus Acidophilus and Postmenopausal Women

Poland90 participantsStarted 2022-02-01

Plain-language summary

This study aims to evaluate the effect of Lactobacillus acidophilus supplementation on calcium status and bone densitometry in postmenopausal women in a randomized, double-blind placebo-controlled study.

Who can participate

Age range45 Years – 70 Years

SexFEMALE

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Inclusion criteria

✓. Women aged 45 to 70 years old with more than one year since last menstruation;
✓. Body mass index (BMI): 27.0 kg/m2 to 34.9 kg/m2;
✓. All female participants who accepted bone densitometry measurement

Exclusion criteria

✕. The secondary form of obesity, the pharmacological treatment for obesity (in the three months before the study), history of bariatric surgery;
✕. Other gastrointestinal disorders, especially: inflammatory bowel diseases, celiac disease, gastritis and duodenitis, pancreatic disorders, gastrointestinal symptoms suggestive of irritable bowel syndrome;
✕. Pharmacotherapy of lipid disorders or hypertension in the three months before enrollment
✕. Clinically significant acute inflammatory process (elevated hsCRP)
✕. Abnormal kidney function (GFR \<60mL/min/1,73m2);
✕. Participation in a body mass management study;
✕. The use of drugs known to modify body mass or food intake;
✕. Hormone replacement therapy;

What they're measuring

Calcium

Timeframe: 2 years

DXA

Timeframe: 2 years

Trial details

NCT IDNCT05332626

SponsorPoznan University of Life Sciences

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-07-01

Results submitted2024-11-04

View on ClinicalTrials.gov More Bone Loss trials