A Comparison of Serum and Urine N-telopeptide Marker

Inclusion Criteria: * Consent to participate in the study * Participants limited to subjects in the CCF * Age between and inclusive of 18 and 85 years of age * No gender exclusion * Patients diagnosed with Osteopenia on DEXA scan who have not been on any medical therapy in the past * Presence of normal vitamin D levels, kidney function, and parathyroid hormone levels (per our reference ranges) Exclusion Criteria: * Prior history of medical therapy for osteopenia * Prior radiation therapy * Prior history of bone fracture * History of high risk medication associated with increased risk of fracture * Presence of abnormal vitamin D levels, kidney function, and parathyroid hormone * Pregnancy status (verbal) * Those with medical co-morbidities that increase the risk of fracture will be excluded and these include but are not limited to: rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, diabetes mellitus, hyperparathyroidism, chronic kidney disease, pituitary disease, multiple myeloma, leukemia, lymphoma, thalassemia major, HIV/AIDS, malabsorption, Inflammatory bowel disease, chronic obstructive pulmonary disease, hypogonadism, chronic liver disease, untreated hyperthyroidism, and those with chronic immobility